Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
21
pubmed:dateCreated
1990-7-17
pubmed:abstractText
Hyaluronic acid (hyaluronan or HA) is a major component of connective tissue synthesized by fibroblasts. Some progress has been made in recent years in the understanding of its metabolism, regulation and physiological role. The development of specific and sensitive assay methods has shown that the HA plasma level is increased in a wide variety of disorders. This increase may be due to decrease hepatic clearance, excessive synthesis (systemic sclerosis, inflammatory arthropathies, psoriasis, cancers, etc.), or even to an increased hyaluronidase activity in certain cancers. The major use of HA assays at the moment is in the evaluation of the evolutivity of those diseases where the HA increase relates to their activity. It seems to be of no diagnostic activity, at least for the time being.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0755-4982
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1001-5
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Hyaluronic acid. Usefulness and perspectives of its serum assay].
pubmed:affiliation
Service de Médecine interne, CHU Rouen-Boisguillaume.
pubmed:publicationType
Journal Article, English Abstract, Review