rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1990-6-6
|
pubmed:abstractText |
Quinolinate phosphoribosyl transferase (QPT) activity was not affected when Escherichia coli were treated with hyperbaric oxygen. This result is not in accord with a previous report (Biochem. Biophys. Res. Comm. 91:982-990; 1979) in which the enzyme was shown to be rapidly inactivated in E. Coli exposed to 4.2 atmospheres of oxygen. Our data rule out QPT as a site of oxygen toxicity and suggest other mechanisms for the inhibitory effects of the hyperbaric oxygen on pyridine nucleotide biosynthesis.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0891-5849
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
117-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2139630-Bacterial Proteins,
pubmed-meshheading:2139630-Chromatography, Paper,
pubmed-meshheading:2139630-Escherichia coli,
pubmed-meshheading:2139630-Free Radicals,
pubmed-meshheading:2139630-Hydrogen Peroxide,
pubmed-meshheading:2139630-Hyperbaric Oxygenation,
pubmed-meshheading:2139630-NAD,
pubmed-meshheading:2139630-Niacin,
pubmed-meshheading:2139630-Pentosyltransferases,
pubmed-meshheading:2139630-Quinolinic Acid,
pubmed-meshheading:2139630-Quinolinic Acids
|
pubmed:year |
1990
|
pubmed:articleTitle |
Quinolinate phosphoribosyl transferase is not the oxygen-sensitive site of nicotinamide adenine dinucleotide biosynthesis.
|
pubmed:affiliation |
Department of Biochemistry, Duke University Medical Center, Durham, NC 27710.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|