21392382

Source:http://linkedlifedata.com/resource/pubmed/id/21392382

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0013081, umls-concept:C0072980, umls-concept:C0246415, umls-concept:C0334227, umls-concept:C0596402, umls-concept:C0664336, umls-concept:C0684249, umls-concept:C2362652
pubmed:dateCreated	2011-3-29
pubmed:abstractText	To elucidate whether rapamycin, the inhibitor of mTOR (mammalian target of rapamycin), can potentiate the cytotoxic effect of docetaxel in lung cancer cells and to probe the mechanism underlying such enhancement.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8308647
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/BIRC5 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Inhibitor of Apoptosis Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Sirolimus, http://linkedlifedata.com/resource/pubmed/chemical/Taxoids, http://linkedlifedata.com/resource/pubmed/chemical/docetaxel
pubmed:status	MEDLINE
pubmed:issn	1756-9966
pubmed:author	pubmed-author:FoàVV, pubmed-author:HePingP, pubmed-author:NiuHuiyanH, pubmed-author:WangJiaheJ
pubmed:issnType	Electronic
pubmed:volume	30
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	28
pubmed:dateRevised	2011-7-27
pubmed:meshHeading	pubmed-meshheading:21392382-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:21392382-Apoptosis, pubmed-meshheading:21392382-Cell Line, Tumor, pubmed-meshheading:21392382-Cell Proliferation, pubmed-meshheading:21392382-Cell Survival, pubmed-meshheading:21392382-Gene Expression Regulation, Neoplastic, pubmed-meshheading:21392382-Humans, pubmed-meshheading:21392382-Inhibitor of Apoptosis Proteins, pubmed-meshheading:21392382-Lung Neoplasms, pubmed-meshheading:21392382-Sirolimus, pubmed-meshheading:21392382-Taxoids
pubmed:year	2011
pubmed:articleTitle	Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells.

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