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pubmed:abstractText |
Transforming growth factor-? (TGF-?), fascin, nuclear factor-kappa B (NF-?B) p105, protein-kinase C-zeta (PKC-?), partioning-defective protein-6 (Par-6), E-cadherin and vimentin are tumor promoting molecules through mechanisms involved in cell dedifferentiation. In soft tissue sarcomas, their expression profile is poorly defined and their significance is uncertain. We aimed to investigate the prognostic impact of TGF-?1, NF-?B p105, PKC-?, Par-6?, E-cadherin and vimentin in non-gastrointestinal stromal tumor soft tissue sarcomas (non-GIST STSs).
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