Linked Life Data

21390228

Source:http://linkedlifedata.com/resource/pubmed/id/21390228

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-3-10
pubmed:abstractText
During speaking, auditory feedback is used to adjust vocalizations. The brain systems mediating this integrative ability have been investigated using a wide range of experimental strategies. In this report we examined how vocalization alters speech-sound processing within auditory cortex by directly recording evoked responses to vocalizations and playback stimuli using intracranial electrodes implanted in neurosurgery patients. Several new findings resulted from these high-resolution invasive recordings in human subjects. Suppressive effects of vocalization were found to occur only within circumscribed areas of auditory cortex. In addition, at a smaller number of sites, the opposite pattern was seen; cortical responses were enhanced during vocalization. This increase in activity was reflected in high gamma power changes, but was not evident in the averaged evoked potential waveforms. These new findings support forward models for vocal control in which efference copies of premotor cortex activity modulate sub-regions of auditory cortex.
pubmed:grant
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pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1932-6203
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
e14744
pubmed:dateRevised
2011-10-21
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Human auditory cortical activation during self-vocalization.
pubmed:affiliation
Department of Neurosurgery, University of Iowa, Iowa City, Iowa, United States of America. jeremy-greenlee@uiowa.edu
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, N.I.H., Extramural