Linked Life Data

21390198

Source:http://linkedlifedata.com/resource/pubmed/id/21390198

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-3-10
pubmed:abstractText
At present, the study into inflammatory markers has become a new tool which is most useful for establishing the prognosis of patients with acute coronary syndrome. The inflammatory substrate involved is acute coronary syndrome is extremely complex, with a large number of factors involved both in its activation and its modulation. It is known that C-reactive protein play a key role in the physiopathology of the atherosclerosis. Furthermore, scientific literature reports that the existence of a circadian rhythm in the triggering of cardiovascular accidents can suggest the implication of, or association with these physiological rhythms that show activity peaks at particular times of the day or night. Keeping in mind the potential association between inflammation and circadian rhythm, a better understanding of the kinetics of said markers could lead to improvements in their use in cardiovascular diseases. Considering the diversity of the diurnal variations in the intrinsic properties of the cardiovascular system, these should be kept in mind during the design of in vivo experimental studies. As such, the information available reinforces our opinion when suitably validating the biomarkers and the need to demonstrate their reliability, stability, and lack of variability and standardise the methodology of their measurement.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Feb
pubmed:issn
1949-8462
pubmed:author
pubmed:issnType
Electronic
pubmed:day
26
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-8
pubmed:dateRevised
2011-7-26
pubmed:year
2011
pubmed:articleTitle
Interrelation between arterial inflammation in acute coronary syndrome and circadian variation.
pubmed:affiliation
Alberto Dominguez-Rodriguez, Maria Carrillo-Perez Tome, Department of Cardiology, Hospital Universitario de Canarias, Tenerife, E-38320, Spain.
pubmed:publicationType
Journal Article