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pubmed:abstractText |
Mitochondrial dysfunction and oxidative stress are thought to play important roles in mammalian aging. Resveratrol is a plant-derived polyphenol that exerts diverse antiaging activities, mimicking some of the molecular and functional effects of dietary restriction. This review focuses on the molecular mechanisms underlying the mitochondrial protective effects of resveratrol, which could be exploited for the prevention or amelioration of age-related diseases in the elderly.
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pubmed:affiliation |
Reynolds Oklahoma Center on Aging, Departments of Geriatric Medicine and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, USA. zoltan-ungvari@ouhsc.edu
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural,
Research Support, N.I.H., Intramural
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