Linked Life Data

21377400

Source:http://linkedlifedata.com/resource/pubmed/id/21377400

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-5-23
pubmed:abstractText
In the current study, kinetics of synthesis of 2-phenylvaleronitrile (PVN) was successfully carried out by selective C-alkylation of benzyl cyanide (BC) with n-bromopropane (BP) using aqueous KOH and catalyzed by TBAB under ultrasonic (300W) assisted organic solvent-free conditions. Selective monoalkylation of benzyl cyanide has been achieved by controlling the reaction conditions and has been followed using gas chromatogram. The effects of various parameters such as agitation speed, catalyst concentration, KOH concentration, benzyl cyanide concentration, volume of water, ultrasonic frequency and temperature were studied systematically to understand their influence on the rate of the reaction. The experimental observations are consistent with an interfacial-type process. Further the kinetic results demonstrate clearly, that ultrasonic assisted phase-transfer catalysis significantly increased the reaction rate when compared to silent reactions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1873-2828
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1241-8
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Sonocatalyzed synthesis of 2-phenylvaleronitrile under controlled reaction conditions--a kinetic study.
pubmed:affiliation
Department of Environmental Engineering, Safety and Health, Hungkuang University, Shalu, Taichung County, Taiwan, Taiwan, ROC.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't