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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-3-7
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pubmed:abstractText |
Over the last 20 years a number of small trials have reported that spironolactone effectively prevents acute mountain sickness (AMS), but to date there have been no large randomized trials investigating the efficacy of spironolactone in prevention of AMS. Hence, a prospective, double-blind, randomized, placebo-controlled trial was conducted to evaluate the efficacy of spironolactone in the prevention of AMS.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1545-1534
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pubmed:author |
pubmed-author:AlexanderHattie DHD,
pubmed-author:BasnyatBuddhaB,
pubmed-author:FarrarJeremyJ,
pubmed-author:GertschJeffreyJ,
pubmed-author:HalversonStephenS,
pubmed-author:HolckPeter SPS,
pubmed-author:JoshiAnipA,
pubmed-author:KarambayJamieJ,
pubmed-author:KhanalSubhashS,
pubmed-author:MorrisseyCandiceC,
pubmed-author:PowellSkipS,
pubmed-author:PunMatiramM,
pubmed-author:SPACE Trial Group,
pubmed-author:ShankarRaviR,
pubmed-author:SteifMikeM,
pubmed-author:StoneAllysonA,
pubmed-author:SzawarskiPiotrP,
pubmed-author:ThompsonBeth HBH
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pubmed:copyrightInfo |
Copyright © 2011 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-22
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pubmed:meshHeading |
pubmed-meshheading:21377114-Acetazolamide,
pubmed-meshheading:21377114-Adult,
pubmed-meshheading:21377114-Altitude Sickness,
pubmed-meshheading:21377114-Double-Blind Method,
pubmed-meshheading:21377114-Female,
pubmed-meshheading:21377114-Headache,
pubmed-meshheading:21377114-Humans,
pubmed-meshheading:21377114-Male,
pubmed-meshheading:21377114-Mountaineering,
pubmed-meshheading:21377114-Nepal,
pubmed-meshheading:21377114-Oxygen,
pubmed-meshheading:21377114-Prospective Studies,
pubmed-meshheading:21377114-Spironolactone,
pubmed-meshheading:21377114-Treatment Outcome
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pubmed:year |
2011
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pubmed:articleTitle |
Spironolactone does not prevent acute mountain sickness: a prospective, double-blind, randomized, placebo-controlled trial by SPACE Trial Group (spironolactone and acetazolamide trial in the prevention of acute mountain sickness group).
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pubmed:affiliation |
Nepal International Clinic, Kathmandu, Nepal.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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