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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-5-23
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pubmed:abstractText |
The microRNA-29 (miR-29) family has emerged, in various tissues, as a key modulator of extracellular matrix (ECM) homeostasis. In this study, the authors investigate the role of the miR-29 family in the regulation of ECM synthesis in the trabecular meshwork (TM) under basal and TGF-?2 stimulatory conditions.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/6,7-dimethyl-2-(2E)-3-(1-methyl-2-ph...,
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Matrix Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Isoquinolines,
http://linkedlifedata.com/resource/pubmed/chemical/MIRN29 microRNA, human,
http://linkedlifedata.com/resource/pubmed/chemical/MicroRNAs,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/SMAD3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Smad3 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1552-5783
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3391-7
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pubmed:dateRevised |
2011-11-1
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pubmed:meshHeading |
pubmed-meshheading:21330653-Adolescent,
pubmed-meshheading:21330653-Adult,
pubmed-meshheading:21330653-Aged,
pubmed-meshheading:21330653-Cell Line,
pubmed-meshheading:21330653-Child,
pubmed-meshheading:21330653-Extracellular Matrix,
pubmed-meshheading:21330653-Extracellular Matrix Proteins,
pubmed-meshheading:21330653-Gene Expression,
pubmed-meshheading:21330653-Humans,
pubmed-meshheading:21330653-Immunoblotting,
pubmed-meshheading:21330653-Isoquinolines,
pubmed-meshheading:21330653-MicroRNAs,
pubmed-meshheading:21330653-Middle Aged,
pubmed-meshheading:21330653-Pyridines,
pubmed-meshheading:21330653-Pyrroles,
pubmed-meshheading:21330653-Recombinant Proteins,
pubmed-meshheading:21330653-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:21330653-Smad3 Protein,
pubmed-meshheading:21330653-Tissue Donors,
pubmed-meshheading:21330653-Trabecular Meshwork,
pubmed-meshheading:21330653-Transfection,
pubmed-meshheading:21330653-Transforming Growth Factor beta
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pubmed:year |
2011
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pubmed:articleTitle |
Coordinated regulation of extracellular matrix synthesis by the microRNA-29 family in the trabecular meshwork.
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pubmed:affiliation |
Department of Ophthalmology, Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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