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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0019704,
umls-concept:C0034656,
umls-concept:C0035668,
umls-concept:C0178539,
umls-concept:C0286651,
umls-concept:C0392760,
umls-concept:C0439662,
umls-concept:C0441889,
umls-concept:C0444956,
umls-concept:C0547047,
umls-concept:C0936233,
umls-concept:C1274040,
umls-concept:C1696465,
umls-concept:C1879547,
umls-concept:C2745888
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|
pubmed:issue |
6
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|
pubmed:dateCreated |
2011-2-23
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|
pubmed:abstractText |
3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors (statins) exhibit antiviral activity against human immunodeficiency virus type 1 (HIV-1) in vitro and may modulate the immune response to HIV infection. Studies evaluating the antiviral activity of statins have yielded conflicting results.
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pubmed:grant |
|
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pubmed:commentsCorrections |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Mar
|
|
pubmed:issn |
1537-6613
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pubmed:author |
pubmed-author:BavaroMaryM,
pubmed-author:BrandtCarolynC,
pubmed-author:Crum-CianfloneNancyN,
pubmed-author:DeckerCatherine FCF,
pubmed-author:FollmannDeanD,
pubmed-author:GanesanAnuradhaA,
pubmed-author:HigginsJeanetteJ,
pubmed-author:MaldarelliFrankF,
pubmed-author:MetcalfJuliaJ,
pubmed-author:QinJingJ,
pubmed-author:RehmCatherineC,
pubmed-author:SklarPeterP,
pubmed-author:TaskerSybilS,
pubmed-author:VitaJeanJ
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|
pubmed:issnType |
Electronic
|
|
pubmed:day |
15
|
|
pubmed:volume |
203
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
756-64
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pubmed:meshHeading |
pubmed-meshheading:21325137-Adult,
pubmed-meshheading:21325137-CD4-Positive T-Lymphocytes,
pubmed-meshheading:21325137-CD8-Positive T-Lymphocytes,
pubmed-meshheading:21325137-Cross-Over Studies,
pubmed-meshheading:21325137-Double-Blind Method,
pubmed-meshheading:21325137-HIV Infections,
pubmed-meshheading:21325137-HIV-1,
pubmed-meshheading:21325137-Heptanoic Acids,
pubmed-meshheading:21325137-Humans,
pubmed-meshheading:21325137-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:21325137-Male,
pubmed-meshheading:21325137-Placebos,
pubmed-meshheading:21325137-Pyrroles,
pubmed-meshheading:21325137-RNA, Viral
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pubmed:year |
2011
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pubmed:articleTitle |
High dose atorvastatin decreases cellular markers of immune activation without affecting HIV-1 RNA levels: results of a double-blind randomized placebo controlled clinical trial.
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pubmed:affiliation |
Division of Infectious Diseases, National Naval Medical Center, Uniformed Services University, Bethesda, Maryland, USA. anuradha.ganesan@med.navy.mil
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Randomized Controlled Trial,
Multicenter Study,
Research Support, N.I.H., Extramural
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