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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-3-28
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pubmed:abstractText |
If tobacco-related carcinogens are not inactivated or extruded from the cell, they can damage the DNA. Single nucleotide polymorphisms (SNPs) in genes involved in tobacco metabolism, DNA repair, and multidrug resistance have been related to lung cancer susceptibility. We examined 13 SNPs in 10 of these genes and correlated the results with time to progression (TTP) and overall survival (OS) in 71 smoker or former smoker patients with resected non-small-cell lung cancer (NSCLC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1095-8673
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pubmed:author |
pubmed-author:CampayoMarcM,
pubmed-author:CarcerenyEnricE,
pubmed-author:CasasFrancescF,
pubmed-author:DiazTaniaT,
pubmed-author:GelBernatB,
pubmed-author:GimferrerJosep MariaJM,
pubmed-author:MarradesRamon MRM,
pubmed-author:MonzoMarianoM,
pubmed-author:NavarroAlfonsA,
pubmed-author:RamirezJoseJ,
pubmed-author:ViñolasNuriaN
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
167
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e5-12
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pubmed:meshHeading |
pubmed-meshheading:21324488-Adult,
pubmed-meshheading:21324488-Aged,
pubmed-meshheading:21324488-Aged, 80 and over,
pubmed-meshheading:21324488-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:21324488-DNA, Neoplasm,
pubmed-meshheading:21324488-DNA Repair,
pubmed-meshheading:21324488-Female,
pubmed-meshheading:21324488-Humans,
pubmed-meshheading:21324488-Kaplan-Meier Estimate,
pubmed-meshheading:21324488-Lung Neoplasms,
pubmed-meshheading:21324488-Male,
pubmed-meshheading:21324488-Middle Aged,
pubmed-meshheading:21324488-Multivariate Analysis,
pubmed-meshheading:21324488-Polymorphism, Single Nucleotide,
pubmed-meshheading:21324488-Prognosis,
pubmed-meshheading:21324488-Retrospective Studies,
pubmed-meshheading:21324488-Survival Rate,
pubmed-meshheading:21324488-Tobacco
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pubmed:year |
2011
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pubmed:articleTitle |
Single nucleotide polymorphisms in tobacco metabolism and DNA repair genes and prognosis in resected non-small-cell lung cancer.
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pubmed:affiliation |
Department of Medical Oncology, ICMHO, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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