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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2011-3-25
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pubmed:databankReference |
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pubmed:abstractText |
ADX10059, a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator, has been shown to reduce gastro-oesophageal reflux events and oesophageal acid exposure in patients with gastro-oesophageal reflux disease (GERD) and healthy subjects.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1365-2036
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pubmed:author |
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pubmed:copyrightInfo |
© 2011 Blackwell Publishing Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
911-21
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pubmed:meshHeading |
pubmed-meshheading:21320138-Adult,
pubmed-meshheading:21320138-Aged,
pubmed-meshheading:21320138-Allosteric Regulation,
pubmed-meshheading:21320138-Double-Blind Method,
pubmed-meshheading:21320138-Esophageal pH Monitoring,
pubmed-meshheading:21320138-Female,
pubmed-meshheading:21320138-Gastroesophageal Reflux,
pubmed-meshheading:21320138-Heartburn,
pubmed-meshheading:21320138-Humans,
pubmed-meshheading:21320138-Hydrogen-Ion Concentration,
pubmed-meshheading:21320138-Male,
pubmed-meshheading:21320138-Middle Aged,
pubmed-meshheading:21320138-Postprandial Period,
pubmed-meshheading:21320138-Proton Pump Inhibitors,
pubmed-meshheading:21320138-Randomized Controlled Trials as Topic,
pubmed-meshheading:21320138-Receptors, Metabotropic Glutamate,
pubmed-meshheading:21320138-Treatment Outcome
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pubmed:year |
2011
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pubmed:articleTitle |
Randomised clinical trial: effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease.
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pubmed:affiliation |
Gastroenterology Department, CHU Bordeaux, Saint André Hospital, and Université Victor Segalen Bordeaux 2, Bordeaux, France.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Multicenter Study
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