rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2011-3-7
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pubmed:databankReference |
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pubmed:abstractText |
Axitinib is a potent, selective inhibitor of vascular endothelial growth factor (VEGF) receptors 1, 2, and 3. A randomised phase 2 trial of gemcitabine with or without axitinib in advanced pancreatic cancer suggested increased overall survival in axitinib-treated patients. On the basis of these results, we aimed to assess the effect of treatment with gemcitabine plus axitinib on overall survival in a phase 3 trial.
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pubmed:commentsCorrections |
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1474-5488
|
pubmed:author |
pubmed-author:BennounaJaafarJ,
pubmed-author:BycottPaulP,
pubmed-author:FunakoshiAkihiroA,
pubmed-author:FuruseJunjiJ,
pubmed-author:IokaTatsuyaT,
pubmed-author:KimSinilS,
pubmed-author:KindlerHedy LHL,
pubmed-author:LétourneauRichardR,
pubmed-author:OhkawaShinichiS,
pubmed-author:OkusakaTakujiT,
pubmed-author:ParkYoung SukYS,
pubmed-author:RicartAlejandro DAD,
pubmed-author:RichelDirk JDJ,
pubmed-author:SpringettGregory MGM,
pubmed-author:TraskPeter CPC,
pubmed-author:Van CutsemEricE,
pubmed-author:WasanHarpreet SHS
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
256-62
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pubmed:meshHeading |
pubmed-meshheading:21306953-Adenocarcinoma,
pubmed-meshheading:21306953-Adult,
pubmed-meshheading:21306953-Aged,
pubmed-meshheading:21306953-Aged, 80 and over,
pubmed-meshheading:21306953-Angiogenesis Inhibitors,
pubmed-meshheading:21306953-Deoxycytidine,
pubmed-meshheading:21306953-Double-Blind Method,
pubmed-meshheading:21306953-Female,
pubmed-meshheading:21306953-Humans,
pubmed-meshheading:21306953-Imidazoles,
pubmed-meshheading:21306953-Indazoles,
pubmed-meshheading:21306953-Male,
pubmed-meshheading:21306953-Middle Aged,
pubmed-meshheading:21306953-Pancreatic Neoplasms,
pubmed-meshheading:21306953-Survival Analysis
|
pubmed:year |
2011
|
pubmed:articleTitle |
Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study.
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pubmed:affiliation |
University of Chicago Comprehensive Cancer Center, Chicago, IL 60637, USA. hkindler@medicine.bsd.uchicago.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase III
|