Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-4-21
pubmed:abstractText
Tissue kallikrein, a widely used vasodilator for the treatment of hypertension and peripheral circulatory disorder, acts by releasing kinin, a potent vasodilator peptide. To identify the role of tissue kallikrein in retinal neovascularization, we investigated the antiangiogenic effect by using an in vitro and in vivo angiogenesis model.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1524-4636
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1041-8
pubmed:meshHeading
pubmed-meshheading:21293011-Aged, pubmed-meshheading:21293011-Amino Acid Sequence, pubmed-meshheading:21293011-Angiogenesis Inhibitors, pubmed-meshheading:21293011-Animals, pubmed-meshheading:21293011-Blotting, Western, pubmed-meshheading:21293011-Case-Control Studies, pubmed-meshheading:21293011-Cell Movement, pubmed-meshheading:21293011-Cell Proliferation, pubmed-meshheading:21293011-Cells, Cultured, pubmed-meshheading:21293011-Coculture Techniques, pubmed-meshheading:21293011-Diabetic Retinopathy, pubmed-meshheading:21293011-Disease Models, Animal, pubmed-meshheading:21293011-Endothelial Cells, pubmed-meshheading:21293011-Extracellular Signal-Regulated MAP Kinases, pubmed-meshheading:21293011-Female, pubmed-meshheading:21293011-Humans, pubmed-meshheading:21293011-Injections, Subcutaneous, pubmed-meshheading:21293011-Male, pubmed-meshheading:21293011-Mass Spectrometry, pubmed-meshheading:21293011-Mice, pubmed-meshheading:21293011-Mice, Inbred C57BL, pubmed-meshheading:21293011-Middle Aged, pubmed-meshheading:21293011-Molecular Sequence Data, pubmed-meshheading:21293011-Phosphorylation, pubmed-meshheading:21293011-Protein Processing, Post-Translational, pubmed-meshheading:21293011-Rats, pubmed-meshheading:21293011-Retinal Neovascularization, pubmed-meshheading:21293011-Retinal Vessels, pubmed-meshheading:21293011-Time Factors, pubmed-meshheading:21293011-Tissue Kallikreins, pubmed-meshheading:21293011-Up-Regulation, pubmed-meshheading:21293011-Vascular Endothelial Growth Factor A, pubmed-meshheading:21293011-Vascular Endothelial Growth Factor Receptor-2, pubmed-meshheading:21293011-Vitreous Body, pubmed-meshheading:21293011-p38 Mitogen-Activated Protein Kinases
pubmed:year
2011
pubmed:articleTitle
Tissue kallikrein inhibits retinal neovascularization via the cleavage of vascular endothelial growth factor-165.
pubmed:affiliation
Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
pubmed:publicationType
Journal Article