rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-5-4
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pubmed:abstractText |
Systemic sclerosis (SSc) is characterised by vasculopathy, an aberrantly activated immune system and excessive extracellular matrix deposition. Inflammatory chemokines control migration of cells to sites of tissue damage; their removal from inflamed sites is essential for resolution of the inflammatory response. The atypical chemokine receptor D6 has a critical role in this physiological balance. To explore potential deregulation of this system in SSc, inflammatory chemokine and D6 expression were compared with that in healthy controls (HC).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1468-2060
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pubmed:author |
pubmed-author:BaldwinHelen MHM,
pubmed-author:BoninoClaudiaC,
pubmed-author:CodulloVeronicaV,
pubmed-author:FraserAlasdair RAR,
pubmed-author:GilmourAshleyA,
pubmed-author:GrahamGerard JGJ,
pubmed-author:HueberAxel JAJ,
pubmed-author:McInnesIain BIB,
pubmed-author:MontecuccoCarlomaurizioC,
pubmed-author:SinghMark DMD,
pubmed-author:WilsonCatherineC
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pubmed:issnType |
Electronic
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1115-21
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pubmed:meshHeading |
pubmed-meshheading:21285114-Aged,
pubmed-meshheading:21285114-Case-Control Studies,
pubmed-meshheading:21285114-Chemokines,
pubmed-meshheading:21285114-Female,
pubmed-meshheading:21285114-Humans,
pubmed-meshheading:21285114-Inflammation Mediators,
pubmed-meshheading:21285114-Leukocytes,
pubmed-meshheading:21285114-Ligands,
pubmed-meshheading:21285114-Male,
pubmed-meshheading:21285114-Middle Aged,
pubmed-meshheading:21285114-Receptors, CCR10,
pubmed-meshheading:21285114-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:21285114-Scleroderma, Systemic,
pubmed-meshheading:21285114-Up-Regulation
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pubmed:year |
2011
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pubmed:articleTitle |
An investigation of the inflammatory cytokine and chemokine network in systemic sclerosis.
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pubmed:affiliation |
Institute of Infection, Immunity and Infl ammation, University of Glasgow, Glasgow, UK. veronicacodullo@yahoo.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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