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rdf:type |
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lifeskim:mentions |
umls-concept:C0005768,
umls-concept:C0030705,
umls-concept:C0242422,
umls-concept:C0277785,
umls-concept:C0332120,
umls-concept:C0332281,
umls-concept:C0521451,
umls-concept:C0600688,
umls-concept:C1414649,
umls-concept:C1519595,
umls-concept:C1706937
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pubmed:issue |
5
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pubmed:dateCreated |
2011-5-10
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pubmed:abstractText |
Our previous results showed that both gray zone and lower end premutation range (40-85 repeats) fragile X mental retardation 1 (FMR1) alleles were more common among males with parkinsonism than in the general population. This study aimed to determine whether these alleles have a significant role in the manifestations and pathogenesis of parkinsonian disorders.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1530-0366
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pubmed:author |
pubmed-author:BuiQuang MQM,
pubmed-author:EvansAndrewA,
pubmed-author:FrancisDavidD,
pubmed-author:GehlingFreyaF,
pubmed-author:GodlerDavid EDE,
pubmed-author:HorneMalcolmM,
pubmed-author:KinsellaGlyndaG,
pubmed-author:KotschetKatya EKE,
pubmed-author:LoeschDanuta ZDZ,
pubmed-author:SlaterHoward RHR,
pubmed-author:StimpsonPaigeP,
pubmed-author:StoreyElsdonE,
pubmed-author:ThorburnDavid RDR,
pubmed-author:TrostNicholasN,
pubmed-author:VennAlisonA
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pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
392-9
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pubmed:meshHeading |
pubmed-meshheading:21270637-Aged,
pubmed-meshheading:21270637-Aged, 80 and over,
pubmed-meshheading:21270637-Alleles,
pubmed-meshheading:21270637-DNA, Mitochondrial,
pubmed-meshheading:21270637-Fragile X Mental Retardation Protein,
pubmed-meshheading:21270637-Genetic Association Studies,
pubmed-meshheading:21270637-Humans,
pubmed-meshheading:21270637-Male,
pubmed-meshheading:21270637-Middle Aged,
pubmed-meshheading:21270637-Motor Activity,
pubmed-meshheading:21270637-Parkinsonian Disorders,
pubmed-meshheading:21270637-RNA, Messenger,
pubmed-meshheading:21270637-Transcription, Genetic,
pubmed-meshheading:21270637-Trinucleotide Repeat Expansion
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pubmed:year |
2011
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pubmed:articleTitle |
Evidence for the toxicity of bidirectional transcripts and mitochondrial dysfunction in blood associated with small CGG expansions in the FMR1 gene in patients with parkinsonism.
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pubmed:affiliation |
School of Psychological Science, La Trobe University, Melbourne, Victoria, Australia. d.loesch@latrobe.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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