Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-2-25
pubmed:abstractText
The effect of Neisseria meningitidis group A and C polysaccharide vaccine on nasopharyngeal carriage was studied in Italian army recruits. Throat swabs were cultured for N. meningitidis at the time of vaccination (one week after entry to service) and again three weeks later in a follow-up cohort of 98 men. At the first survey the overall carriage rate was 32% with 9% of isolates due to serogroup C, none to serogroup A and 17% to serogroup Y. At the second survey the overall carriage rate reached 52% (P less than 0.01); no isolate belonged to serogroup A or C, while serogroup Y reached 40% (P less than 0.01). The cumulative carriage rate was 65%. Out of the 64 carriers during the whole study period, only 7 (11%) belonged to the same serogroup during the two different surveys. The vaccination appears to influence the carriage rate of meningococcal specific serogroups. The inhibition of serogroups A and C is, however, offset by an increased prevalence of meningococci belonging to serogroup Y.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0391-5352
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
225-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
The effect of meningococcal group A and C polysaccharide vaccine on nasopharyngeal carrier state.
pubmed:affiliation
Laboratorio di Epidemiologia, Istituto Superiore di Sanità, Roma, Italy.
pubmed:publicationType
Journal Article