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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-2-20
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pubmed:abstractText |
The Drosophila melanogaster z600 gene is zygotically expressed with gene transcripts accumulating transiently during early embryogenesis. Based on nucleotide sequence analysis, z600 is predicted to encode a small, basic, histone-like protein. Antibodies generated against a beta-galactosidase::z600 fusion protein immunoprecipitated the z600 in vitro translation product and detected a z600 protein present predominantly in 2- to 4-h embryos. We localized the z600 protein in whole-amount embryos by indirect immunofluorescence. These studies show that the protein is located in the nucleus and associated with chromatin in the syncytial blastoderm.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0378-1119
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
96
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pubmed:geneSymbol |
z600
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
227-32
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2125289-Animals,
pubmed-meshheading:2125289-Antibodies,
pubmed-meshheading:2125289-Blastoderm,
pubmed-meshheading:2125289-Chromatin,
pubmed-meshheading:2125289-Drosophila melanogaster,
pubmed-meshheading:2125289-Fluorescent Antibody Technique,
pubmed-meshheading:2125289-Genes,
pubmed-meshheading:2125289-Nuclear Proteins,
pubmed-meshheading:2125289-Transcription, Genetic
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pubmed:year |
1990
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pubmed:articleTitle |
The Drosophila melanogaster z600 gene encodes a chromatin-associated protein synthesized in the syncytial blastoderm.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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