Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1991-1-24
pubmed:abstractText
To investigate the efficacy of ethacridine lactate by the extra-amniotic route for second trimester pregnancy termination and its associated complications.
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/Abortion, Drug Induced--complications, http://linkedlifedata.com/resource/pubmed/keyword/Abortion, Induced, http://linkedlifedata.com/resource/pubmed/keyword/Asia, http://linkedlifedata.com/resource/pubmed/keyword/Biology, http://linkedlifedata.com/resource/pubmed/keyword/Clinical Research, http://linkedlifedata.com/resource/pubmed/keyword/Comparative Studies, http://linkedlifedata.com/resource/pubmed/keyword/Contraception, http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Usage, http://linkedlifedata.com/resource/pubmed/keyword/Demographic Factors, http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries, http://linkedlifedata.com/resource/pubmed/keyword/Endocrine System, http://linkedlifedata.com/resource/pubmed/keyword/Family Planning, http://linkedlifedata.com/resource/pubmed/keyword/Fertility, http://linkedlifedata.com/resource/pubmed/keyword/Fertility Control, Postconception, http://linkedlifedata.com/resource/pubmed/keyword/Fertility Measurements, http://linkedlifedata.com/resource/pubmed/keyword/INDIA, http://linkedlifedata.com/resource/pubmed/keyword/Method Acceptability, http://linkedlifedata.com/resource/pubmed/keyword/PROSTAGLANDINS, http://linkedlifedata.com/resource/pubmed/keyword/Parity, http://linkedlifedata.com/resource/pubmed/keyword/Physiology, http://linkedlifedata.com/resource/pubmed/keyword/Population, http://linkedlifedata.com/resource/pubmed/keyword/Population Dynamics, http://linkedlifedata.com/resource/pubmed/keyword/Pregnancy, http://linkedlifedata.com/resource/pubmed/keyword/Pregnancy, Second Trimester, http://linkedlifedata.com/resource/pubmed/keyword/Reproduction, http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology, http://linkedlifedata.com/resource/pubmed/keyword/Southern Asia, http://linkedlifedata.com/resource/pubmed/keyword/Studies, http://linkedlifedata.com/resource/pubmed/keyword/Time Factors
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0306-5456
pubmed:author
pubmed:issnType
Print
pubmed:volume
97
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1026-9
pubmed:dateRevised
2010-3-24
pubmed:otherAbstract
PIP: This study investigated the efficacy of ethacridine lactate by the extraamniotic route during 2nd trimester pregnancy termination as well as its associated complications. This retrospective study of 315 women undergoing 2nd trimester terminations over a 3 1/2 year period was based at a teaching hospital in Bombay. Patients received either extraamniotic ethacridine alone or supplemented later with extraamniotic 15-methyl- prostaglandin F2alpha (PGF2alpha). Women were divided into 2 groups--in group 1, 207 women received 150 ml of 0.1% ethacridine lactate injected slowly into the extraamniotic space; in group 2, 108 women had the initial injection supplemented 6 hours later by an extraamniotic injection of 250 mcg (1 ml) of 15-methyl-PGF2alpha. Outcome measures which were evaluated were the occurrence of abortion following the induction procedure and the development of complications such as hemorrhage, infection, and injury to the cervix or uterus. The method was successful in 191 women (92%) in group 1 and in 106 (98%) in group 2. The mean induction-abortion intervals were 35 and 19 hours, respectively (Mann-Whitney U test, p0.001). The corrected complication rate was 10% (30 women), with unplanned uterine evacuation in 6% (20), hemorrhage in 1% (4), and pelvic infection in 4% (14). The authors conclude that the use of extraamniotic ethacridine lactate provides an effective and safe treatment method for 2nd trimester legal abortion. The induction-abortion interval can be appreciably reduced by supplementary PGs.
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Second trimester pregnancy termination using extra-amniotic ethacridine lactate.
pubmed:affiliation
Wadia Maternity Hospital, Bombay, India.
pubmed:publicationType
Journal Article