|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0017687,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0185117,
umls-concept:C0299583,
umls-concept:C0679058,
umls-concept:C1547699,
umls-concept:C2700640,
umls-concept:C2911684
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2011-3-10
|
|
pubmed:abstractText |
Leptin, released by adipocytes, can modulate glucose homeostasis through direct actions on pancreatic alpha and beta cells. Although this hormone rapidly regulates alpha cell exocytosis, its long-term effects on glucagon gene expression are currently unknown.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
1432-0428
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
54
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
843-51
|
|
pubmed:meshHeading |
pubmed-meshheading:21234744-Animals,
pubmed-meshheading:21234744-Blotting, Western,
pubmed-meshheading:21234744-Cell Line,
pubmed-meshheading:21234744-Female,
pubmed-meshheading:21234744-Glucagon,
pubmed-meshheading:21234744-Immunohistochemistry,
pubmed-meshheading:21234744-Islets of Langerhans,
pubmed-meshheading:21234744-Leptin,
pubmed-meshheading:21234744-Mice,
pubmed-meshheading:21234744-Mice, Inbred C57BL,
pubmed-meshheading:21234744-RNA, Small Interfering,
pubmed-meshheading:21234744-Reverse Transcriptase Polymerase Chain Reaction
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Leptin downregulates expression of the gene encoding glucagon in alphaTC1-9 cells and mouse islets.
|
|
pubmed:affiliation |
Instituto de Bioingeniería, Universidad Miguel Hernandez, Avenida de la Universidad, 03202 Elche, Spain.
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
