Source:http://linkedlifedata.com/resource/pubmed/id/21234658
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2011-4-11
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pubmed:abstractText |
The area under the curve (AUC) is commonly used to assess the extent of exposure of a drug. The same concept can be applied to generally assess pharmacodynamic responses and the deviation of a signal from its baseline value. When the initial condition for the response of interest is not zero, there is uncertainty in the true value of the baseline measurement. This necessitates the consideration of the AUC relative to baseline to account for this inherent uncertainty and variability in baseline measurements.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1573-904X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1081-9
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pubmed:dateRevised |
2011-8-10
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pubmed:meshHeading | |
pubmed:year |
2011
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pubmed:articleTitle |
Assessment of pharmacologic area under the curve when baselines are variable.
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pubmed:affiliation |
Biomedical Engineering Department, Rutgers University, 599 Taylor Road, Piscataway, New Jersey 08854, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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