rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2011-2-23
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pubmed:abstractText |
Recent studies indicate that type 2 diabetes is associated with an increased secretion of both hepatic and intestinal lipoproteins, leading to the accumulation of atherogenic triglyceride (TG)-rich lipoproteins. Sitagliptin is a selective inhibitor of dipeptidyl peptidase-4 that has been shown to reduce fasting and postprandial glucose levels in patients with type 2 diabetes presumably through incretin hormone-mediated improvements in islet function. The objective of the present study is to examine the effects of treatment with sitagliptin on postprandial lipid and incretin hormone levels as well as glucose homeostasis in patients with type 2 diabetes.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1463-1326
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pubmed:author |
|
pubmed:copyrightInfo |
© 2011 Blackwell Publishing Ltd.
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pubmed:issnType |
Electronic
|
pubmed:volume |
13
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
366-73
|
pubmed:meshHeading |
pubmed-meshheading:21226820-Diabetes Mellitus, Type 2,
pubmed-meshheading:21226820-Dipeptidyl-Peptidase IV Inhibitors,
pubmed-meshheading:21226820-Female,
pubmed-meshheading:21226820-Humans,
pubmed-meshheading:21226820-Hypoglycemic Agents,
pubmed-meshheading:21226820-Lipoproteins,
pubmed-meshheading:21226820-Male,
pubmed-meshheading:21226820-Middle Aged,
pubmed-meshheading:21226820-Postprandial Period,
pubmed-meshheading:21226820-Pyrazines,
pubmed-meshheading:21226820-Treatment Outcome,
pubmed-meshheading:21226820-Triazoles
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pubmed:year |
2011
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pubmed:articleTitle |
Effect of sitagliptin therapy on postprandial lipoprotein levels in patients with type 2 diabetes.
|
pubmed:affiliation |
Department of Food Sciences, Institute of Nutraceuticals and Functional Foods, Laval University, Quebec City, Québec, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|