21224326

Source:http://linkedlifedata.com/resource/pubmed/id/21224326

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0013080, umls-concept:C0031809, umls-concept:C0032105, umls-concept:C0162326, umls-concept:C0175659, umls-concept:C0222045, umls-concept:C0349674, umls-concept:C0678804, umls-concept:C0917792, umls-concept:C1858460, umls-concept:C2349101, umls-concept:C2603343
pubmed:dateCreated	2011-1-12
pubmed:abstractText	To validate the clinical efficacy and practical feasibility of massively parallel maternal plasma DNA sequencing to screen for fetal trisomy 21 among high risk pregnancies clinically indicated for amniocentesis or chorionic villus sampling.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8900488
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/DNA
pubmed:status	MEDLINE
pubmed:issn	1468-5833
pubmed:author	pubmed-author:AkolekarRanjitR, pubmed-author:Au-YeungSidney K CSK, pubmed-author:ChanK C AllenKC, pubmed-author:ChiuRossa W KRW, pubmed-author:GoAttie T J IAT, pubmed-author:HellerI RIR, pubmed-author:KungYu YYY, pubmed-author:LauElizabeth TET, pubmed-author:LauTze KTK, pubmed-author:LeungTak YTY, pubmed-author:LeungWing CWC, pubmed-author:LoY M DennisYM, pubmed-author:LunFiona M FFM, pubmed-author:MinekawaRyokoR, pubmed-author:NicolaidesKypros HKH, pubmed-author:OudejansCees B MCB, pubmed-author:SunHaoH, pubmed-author:TangMary H YMH, pubmed-author:TangRebecca Y KRY, pubmed-author:ToWilliam W KWW, pubmed-author:WangJunJ, pubmed-author:ZhangXiuqingX, pubmed-author:ZhengYama W LYW, pubmed-author:van VugtJohn M GJM
pubmed:issnType	Electronic
pubmed:volume	342
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	c7401
pubmed:dateRevised	2011-7-20
pubmed:meshHeading	pubmed-meshheading:21224326-Adult, pubmed-meshheading:21224326-Case-Control Studies, pubmed-meshheading:21224326-DNA, pubmed-meshheading:21224326-Down Syndrome, pubmed-meshheading:21224326-Female, pubmed-meshheading:21224326-Humans, pubmed-meshheading:21224326-Karyotyping, pubmed-meshheading:21224326-Male, pubmed-meshheading:21224326-Maternal Age, pubmed-meshheading:21224326-Pregnancy, pubmed-meshheading:21224326-Prenatal Diagnosis, pubmed-meshheading:21224326-ROC Curve, pubmed-meshheading:21224326-Sensitivity and Specificity, pubmed-meshheading:21224326-Sequence Analysis, DNA, pubmed-meshheading:21224326-Sex Determination Processes
pubmed:year	2011
pubmed:articleTitle	Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study.
pubmed:affiliation	Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China.
pubmed:publicationType	Journal Article, Multicenter Study, Validation Studies