|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2011-1-11
|
|
pubmed:abstractText |
In order to identify the binding proteins to anti-resorptive 5-chloro-1-(2,6-dimethylpiperidin-1-yl)-N-tosylpentan-1-imine (1), the chemical affinity matrix for the compound 1 (2b) was designed and synthesized. Using 2b-based chemical proteomics, prohibitin was identified as one of strong binding proteins for 2b.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
1464-3405
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ltd. All rights reserved.
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
15
|
|
pubmed:volume |
21
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
727-9
|
|
pubmed:meshHeading |
pubmed-meshheading:21195613-Amidines,
pubmed-meshheading:21195613-Animals,
pubmed-meshheading:21195613-Bone Density Conservation Agents,
pubmed-meshheading:21195613-Cell Line,
pubmed-meshheading:21195613-Chromatography, Affinity,
pubmed-meshheading:21195613-Mice,
pubmed-meshheading:21195613-Protein Binding,
pubmed-meshheading:21195613-Proteomics,
pubmed-meshheading:21195613-Repressor Proteins,
pubmed-meshheading:21195613-Sulfinic Acids
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Chemical affinity matrix-based identification of prohibitin as a binding protein to anti-resorptive sulfonyl amidine compounds.
|
|
pubmed:affiliation |
Medicinal Chemistry Research Center, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
