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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1990-10-26
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pubmed:abstractText |
Monoclonal Antibody-Antigen Spot Test (McAb-AST) was used for detecting circulating antigen in sera from patients with schistosomiasis japonicum. McAb-AST positive rate in 308 schistosomiasis patients before treatment was 75.97%. Among the patients who had moderate or severe infection, the McAb-AST positive rates were 91.18% or 100% respectively. However, the McAb-AST cross-reactive rates in 123 normal donors, 98 clonorchiasis patients, 50 paragonimiasis patients and 56 patients with other parasitic diseases were 0%, 3.06%, 4%, and 1.79% respectively. 1.3 and 6 months after treatment, the McAb-AST negative-converting rates in patients who had negative results of stool hatching were 98.03%, 100% and 100% respectively. Compared with the results of detection of circulating antibodies, negative-conversion of circulating antigen in the patients with negative stool hatching appeared earlier and the negative-converting rate of circulating antigen was much higher. Therefore, McAb-AST had significant value in clinical practice because of its high sensitivity, specificity and good reproducibility.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0578-1426
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
26-8, 61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading | |
pubmed:year |
1990
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pubmed:articleTitle |
[Detection of circulating antigen in the sera in patients with schistosomiasis using monoclonal antibody testing].
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pubmed:affiliation |
Schistosomiasis Research Laboratory, First Hospital, Chongqing Medical University.
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pubmed:publicationType |
Journal Article,
English Abstract
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