Source:http://linkedlifedata.com/resource/pubmed/id/21174183
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2011-2-4
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pubmed:abstractText |
Postoperative cognitive decline in the elderly has emerged as a major health concern. In addition, there is a growing interest in the potential relationship between general anesthetic exposure and the onset and progression of Alzheimer's disease (AD). The available evidence of a possible association between anesthesia, surgery, and long-term cognitive effects, including AD, deserves consideration. In this review, we summarize the evidence for anesthesia-induced neurotoxicity in the elderly, while highlighting the limitations of existing data, and we put the literature into perspective for the clinician.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1496-8975
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
216-23
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pubmed:meshHeading |
pubmed-meshheading:21174183-Age Factors,
pubmed-meshheading:21174183-Aged,
pubmed-meshheading:21174183-Alzheimer Disease,
pubmed-meshheading:21174183-Anesthetics, General,
pubmed-meshheading:21174183-Animals,
pubmed-meshheading:21174183-Cognition Disorders,
pubmed-meshheading:21174183-Disease Models, Animal,
pubmed-meshheading:21174183-Disease Progression,
pubmed-meshheading:21174183-Humans,
pubmed-meshheading:21174183-Neurotoxicity Syndromes,
pubmed-meshheading:21174183-Postoperative Complications,
pubmed-meshheading:21174183-Species Specificity
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pubmed:year |
2011
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pubmed:articleTitle |
Brief review: anesthetic neurotoxicity in the elderly, cognitive dysfunction and Alzheimer's disease.
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pubmed:affiliation |
Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129-2060, USA.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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