Linked Life Data

21171243

Source:http://linkedlifedata.com/resource/pubmed/id/21171243

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-12-20
pubmed:abstractText
The impact of chemotherapy on a woman's fertility depends on her age and the types and doses of the drugs used. Alkylating agents have the biggest negative impact on ovarian function. A trial is currently examining the use of a GnRH agonist to protect ovarian function. The impact of external radiation therapy and brachytherapy on the ovaries depends on three factors: the patient's age, the dose delivered to the ovaries, and concurrent use of chemotherapy. Ovarian transposition is a simple surgical procedure that can be used in selected cases to reduce the risk of early menopause. Both external and internal radiation has an impact on the uterus, notably by altering its vascularization and by reducing its growth when treatment is delivered during childhood.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0001-4079
pubmed:author
pubmed:issnType
Print
pubmed:volume
194
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
481-92; discussion 492-4, 529-30
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
[Effects of radiotherapy (external and/or internal) and chemotherapy on female fertility].
pubmed:affiliation
Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France. philippe.morice@igr.fr
pubmed:publicationType
Journal Article, English Abstract