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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9-10
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pubmed:dateCreated |
2011-2-21
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pubmed:abstractText |
Fatigue is a common occurrence in cancer patients regardless of tumor type or anti-tumor therapies and is an especially problematic symptom in persons with incurable tumor disease. In rodents, tumor-induced fatigue is associated with a progressive loss of skeletal muscle mass and increased expression of biomarkers of muscle protein degradation. The purpose of the present study was to determine if muscle wasting and expression of biomarkers of muscle protein degradation occur in the hearts of tumor-bearing mice, and if these effects of tumor growth are associated with changes in cardiac function.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/BNip3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/Fbxo32 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Mitochondrial Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Muscle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/SKP Cullin F-Box Protein Ligases
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1879-0631
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
28
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
406-10
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pubmed:meshHeading |
pubmed-meshheading:21167183-Adenocarcinoma,
pubmed-meshheading:21167183-Animals,
pubmed-meshheading:21167183-Biological Markers,
pubmed-meshheading:21167183-Cachexia,
pubmed-meshheading:21167183-Cardiomyopathies,
pubmed-meshheading:21167183-Colonic Neoplasms,
pubmed-meshheading:21167183-Disease Models, Animal,
pubmed-meshheading:21167183-Female,
pubmed-meshheading:21167183-Gene Expression,
pubmed-meshheading:21167183-Membrane Proteins,
pubmed-meshheading:21167183-Mice,
pubmed-meshheading:21167183-Mice, Inbred Strains,
pubmed-meshheading:21167183-Mitochondrial Proteins,
pubmed-meshheading:21167183-Muscle, Skeletal,
pubmed-meshheading:21167183-Muscle Proteins,
pubmed-meshheading:21167183-Myocytes, Cardiac,
pubmed-meshheading:21167183-Neoplasm Transplantation,
pubmed-meshheading:21167183-RNA, Messenger,
pubmed-meshheading:21167183-SKP Cullin F-Box Protein Ligases,
pubmed-meshheading:21167183-Specific Pathogen-Free Organisms
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pubmed:year |
2011
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pubmed:articleTitle |
Myocardial dysfunction in an animal model of cancer cachexia.
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pubmed:affiliation |
College of Nursing, The Ohio State University, United States.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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