Linked Life Data

21151595

Source:http://linkedlifedata.com/resource/pubmed/id/21151595

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-12-14
pubmed:abstractText
To evaluate the possibility of genetic involvement in retinopathy of prematurity (ROP). Although ROP is most often associated with low birthweight and low gestational age, these factors do not necessarily predict the severity of ROP. The possible involvement of other factors, including genetic variants, has been considered. Familial exudative vitreoretinopathy (FEVR) is a hereditary vitreoretinal disorder with clinical manifestations similar to those of ROP. Three genes involving the wingless/int1 (Wnt) receptor signaling pathway-FZD4 for frizzled 4, LRP5 for low-density lipoprotein receptor-related protein 5, and ND for Norrie disease protein-are associated with the development of FEVR.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1090-0535
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2572-7
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Genetic screening of Wnt signaling factors in advanced retinopathy of prematurity.
pubmed:affiliation
Department of Ophthalmology, Nippon Medical School, Tokyo, Japan. mikihira@nms.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't