|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1990-8-13
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|
pubmed:abstractText |
We used the guinea pig as an experimental model to investigate the pathogenicity of Mycobacterium tuberculosis. Sputum samples were injected subcutaneously into guinea pigs and the animals were killed and an autopsy performed after eight weeks. The likelihood of the sputum samples producing tuberculosis in the guinea pig was related to culture positivity rather than to duration of chemotherapy. This study does not support the belief that a change in pathogenicity occurs during treatment of pulmonary tuberculosis.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0903-1936
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
3
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
399-402
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|
pubmed:dateRevised |
2005-11-17
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|
pubmed:meshHeading |
pubmed-meshheading:2114307-Animals,
pubmed-meshheading:2114307-Anti-Bacterial Agents,
pubmed-meshheading:2114307-Antitubercular Agents,
pubmed-meshheading:2114307-Disease Models, Animal,
pubmed-meshheading:2114307-Drug Therapy, Combination,
pubmed-meshheading:2114307-Ethambutol,
pubmed-meshheading:2114307-Fluorescent Antibody Technique,
pubmed-meshheading:2114307-Guinea Pigs,
pubmed-meshheading:2114307-Humans,
pubmed-meshheading:2114307-Injections, Subcutaneous,
pubmed-meshheading:2114307-Isoniazid,
pubmed-meshheading:2114307-Mycobacterium tuberculosis,
pubmed-meshheading:2114307-Rifampin,
pubmed-meshheading:2114307-Sputum,
pubmed-meshheading:2114307-Tuberculosis, Pulmonary
|
|
pubmed:year |
1990
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|
pubmed:articleTitle |
The pathogenicity of Mycobacterium tuberculosis during chemotherapy.
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|
pubmed:affiliation |
Peamount Hospital, Newcastle, Co. Dublin, Ireland.
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|
pubmed:publicationType |
Journal Article
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