Source:http://linkedlifedata.com/resource/pubmed/id/21140599
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2010-12-8
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pubmed:abstractText |
Theiler’s murine encephalomyelitis virus is divided into two subgroups, TO and GDVII, inducing subgroup-specific diseases. In order to investigate the role(s) of nonstructural proteins of TMEV, L and L(?), leaders of two subgroups, were separately expressed with or without L(?) in BHK-21 cells. Expression of L increased the number of apoptotic cells. L(?)/BHK-21 cells constitutively expressing L(?) showed the decrease in cell death induced by L. These results suggest that L and L(?) regulate apoptosis during viral infection and contribute to TMEV subgroup-specific biological activities.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0385-5600
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
639-43
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
Opposite effects of two nonstructural proteins of Theiler’s murine encephalomyelitis virus regulates apoptotic cell death in BHK-21 cells.
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pubmed:affiliation |
Department of Microbiology, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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