Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2010-12-8
pubmed:abstractText
Theiler’s murine encephalomyelitis virus is divided into two subgroups, TO and GDVII, inducing subgroup-specific diseases. In order to investigate the role(s) of nonstructural proteins of TMEV, L and L(?), leaders of two subgroups, were separately expressed with or without L(?) in BHK-21 cells. Expression of L increased the number of apoptotic cells. L(?)/BHK-21 cells constitutively expressing L(?) showed the decrease in cell death induced by L. These results suggest that L and L(?) regulate apoptosis during viral infection and contribute to TMEV subgroup-specific biological activities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0385-5600
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
639-43
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Opposite effects of two nonstructural proteins of Theiler’s murine encephalomyelitis virus regulates apoptotic cell death in BHK-21 cells.
pubmed:affiliation
Department of Microbiology, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't