Linked Life Data

2113760

Source:http://linkedlifedata.com/resource/pubmed/id/2113760

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
1990-7-31
pubmed:abstractText
Serially cultivated rat middle ear epithelium was studied under exposure to various concentrations of carbon dioxide. Three experiments were performed exposing the epithelium to a gaseous environment containing 5 or 10% CO2 or to an atmosphere almost devoid of CO2. Oxygen was maintained constant at 20% and nitrogen was additionally supplied. Cells exposed at 0% CO2 showed a remarkably different morphology compared with the cultures at 5 and 10% CO2, cells could become extremely large at 0% CO2, also showing a great variation in shape and cell size within the culture. Proliferation was significantly impaired at 0% CO2 vis-à-vis the 5 and 10% experiments. Terminal differentiation, however, was not influenced by the different CO2 concentrations, indicating that in vitro, variation in CO2 concentration is of no importance regarding a possible differentiation of middle ear epithelium into a cornifying epithelium.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-6489
pubmed:author
pubmed:issnType
Print
pubmed:volume
109
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
431-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
The effect of external stimuli on rat middle ear epithelium in culture. Extracellular carbon dioxide concentration.
pubmed:affiliation
ENT Department, University Hospital Leiden, The Netherlands.
pubmed:publicationType
Journal Article, In Vitro