Source:http://linkedlifedata.com/resource/pubmed/id/21124905
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2010-12-2
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pubmed:abstractText |
BC RNAs and the fragile X mental retardation protein (FMRP) are translational repressors that have been implicated in the control of local protein synthesis at the synapse. Work with BC1 and Fmr1 animal models has revealed that phenotypical consequences resulting from the absence of either BC1 RNA or FMRP are remarkably similar. To establish functional interactions between BC1 RNA and FMRP is important for our understanding of how local protein synthesis regulates neuronal excitability.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e15509
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pubmed:meshHeading |
pubmed-meshheading:21124905-Animals,
pubmed-meshheading:21124905-Avoidance Learning,
pubmed-meshheading:21124905-Brain,
pubmed-meshheading:21124905-CA3 Region, Hippocampal,
pubmed-meshheading:21124905-Electrophysiology,
pubmed-meshheading:21124905-Female,
pubmed-meshheading:21124905-Fragile X Mental Retardation Protein,
pubmed-meshheading:21124905-Male,
pubmed-meshheading:21124905-Mice,
pubmed-meshheading:21124905-Mice, 129 Strain,
pubmed-meshheading:21124905-Mice, Inbred C57BL,
pubmed-meshheading:21124905-Mice, Knockout,
pubmed-meshheading:21124905-Nerve Net,
pubmed-meshheading:21124905-RNA, Small Cytoplasmic
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pubmed:year |
2010
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pubmed:articleTitle |
Regulatory BC1 RNA and the fragile X mental retardation protein: convergent functionality in brain.
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pubmed:affiliation |
Department of Physiology and Pharmacology, The Robert F. Furchgott Center for Neural and Behavioral Science, State University of New York Health Science Center at Brooklyn, Brooklyn, New York, USA. jun.zhong@downstate.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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