Linked Life Data

21108680

Source:http://linkedlifedata.com/resource/pubmed/id/21108680

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-11-26
pubmed:abstractText
The objectives of this study were to detect effective genetic polymorphisms of bovine growth hormone (bGH) gene associated with calf weight in Japanese Black cattle. Fifty-eight sires and 47 breeding cows were used to detect the polymorphisms in exons by single-strand conformation polymorphism (SSCP). Four homozygous and six heterozygous SSCP genotypes were identified in exon 5. Although each single nucleotide polymorphism (SNP) had been reported, these genotypes were caused by three SNPs at the nucleotide positions 2141, 2277 and 2291. Four haplotypes C-C-A, G-C-A, C-C-C and G-T-A were newly identified. It was suggested that other haplotypes not detected in this study may not exist, considering the allele frequencies reported in Bos taurus and Bos indicus, and the migrating process of native Japanese cattle. Thereafter, we examined associations between the detected polymorphic sites in exon 5 by PCR - restriction fragment length polymorphism and calf weight using 53 breeding dams and 135 calves. The birth weights of calves with haplotype G-C-A are significantly lighter and calves' weights produced by cows with such haplotype are also lighter at 30 days old, using regression analysis. Although further research is necessary, these results may serve as a useful criterion to select breeding stocks, especially in maternal abilities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1740-0929
pubmed:author
pubmed:copyrightInfo
© 2010 The Authors. Journal compilation © 2010 Japanese Society of Animal Science.
pubmed:issnType
Electronic
pubmed:volume
81
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
623-9
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Polymorphisms in growth hormone gene and their associations with calf weight in Japanese Black cattle.
pubmed:affiliation
University of Miyazaki, Japan. t-ishida@cc.miyazaki-u.ac.jp
pubmed:publicationType
Journal Article