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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-11-24
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pubmed:abstractText |
Patients with prosthesis-patient mismatch (PPM) continue to show some degrees of left ventricular hypertrophy after aortic valve replacement for aortic stenosis. The renin-angiotensin system plays a major role in promoting and sustaining hypertrophy. In a controlled, randomized study, we tested the hypothesis that the combination of angiotensin-converting enzyme inhibitors (ACEi) plus angiotensin II receptor blocker (ARB) can be more effective in decreasing hypertrophy than a largely employed association such as ACEi plus ß-blockers in PPM patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1552-6259
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1899-903; discussion 1903
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pubmed:meshHeading |
pubmed-meshheading:21095333-Adrenergic beta-1 Receptor Antagonists,
pubmed-meshheading:21095333-Aged,
pubmed-meshheading:21095333-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:21095333-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:21095333-Aortic Valve Stenosis,
pubmed-meshheading:21095333-Benzimidazoles,
pubmed-meshheading:21095333-Blood Pressure,
pubmed-meshheading:21095333-Dose-Response Relationship, Drug,
pubmed-meshheading:21095333-Drug Therapy, Combination,
pubmed-meshheading:21095333-Echocardiography,
pubmed-meshheading:21095333-Female,
pubmed-meshheading:21095333-Follow-Up Studies,
pubmed-meshheading:21095333-Heart Valve Prosthesis,
pubmed-meshheading:21095333-Heart Ventricles,
pubmed-meshheading:21095333-Humans,
pubmed-meshheading:21095333-Hypertrophy, Left Ventricular,
pubmed-meshheading:21095333-Male,
pubmed-meshheading:21095333-Metoprolol,
pubmed-meshheading:21095333-Prosthesis Design,
pubmed-meshheading:21095333-Prosthesis Failure,
pubmed-meshheading:21095333-Ramipril,
pubmed-meshheading:21095333-Renin-Angiotensin System,
pubmed-meshheading:21095333-Retrospective Studies,
pubmed-meshheading:21095333-Tetrazoles,
pubmed-meshheading:21095333-Treatment Outcome
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pubmed:year |
2010
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pubmed:articleTitle |
Dual renin-angiotensin system blockade for patients with prosthesis-patient mismatch.
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pubmed:affiliation |
Department of Cardiac Surgery, II School of Medicine, University of Rome La Sapienza, Policlinico S. Andrea, Rome, Italy. u2benedetto@libero.it
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial
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