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rdf:type |
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lifeskim:mentions |
umls-concept:C0001779,
umls-concept:C0025219,
umls-concept:C0030685,
umls-concept:C0033139,
umls-concept:C0087111,
umls-concept:C0220825,
umls-concept:C0391871,
umls-concept:C0439590,
umls-concept:C0443252,
umls-concept:C0680255,
umls-concept:C0871261,
umls-concept:C1283071,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1963578,
umls-concept:C2911692
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pubmed:issue |
1
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pubmed:dateCreated |
2010-12-17
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pubmed:databankReference |
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pubmed:abstractText |
The authors recently reported on efficacy and safety of prolonged-release melatonin formulation (PRM; Circadin 2? mg) in elderly insomnia patients. The age cut-off for response to PRM and the long-term maintenance of efficacy and safety were further evaluated by looking at the total cohort (age 18-80 years) from that study and subsets of patients aged 18-54 and 55-80 years (for whom the drug is currently indicated).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1473-4877
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
87-98
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pubmed:meshHeading |
pubmed-meshheading:21091391-Adolescent,
pubmed-meshheading:21091391-Adult,
pubmed-meshheading:21091391-Age Distribution,
pubmed-meshheading:21091391-Aged,
pubmed-meshheading:21091391-Aged, 80 and over,
pubmed-meshheading:21091391-Delayed-Action Preparations,
pubmed-meshheading:21091391-Drug Administration Schedule,
pubmed-meshheading:21091391-Female,
pubmed-meshheading:21091391-Follow-Up Studies,
pubmed-meshheading:21091391-Humans,
pubmed-meshheading:21091391-Male,
pubmed-meshheading:21091391-Melatonin,
pubmed-meshheading:21091391-Middle Aged,
pubmed-meshheading:21091391-Placebos,
pubmed-meshheading:21091391-Sleep Initiation and Maintenance Disorders,
pubmed-meshheading:21091391-Time Factors,
pubmed-meshheading:21091391-Treatment Outcome,
pubmed-meshheading:21091391-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Prolonged release melatonin in the treatment of primary insomnia: evaluation of the age cut-off for short- and long-term response.
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pubmed:affiliation |
CPS Research, Glasgow, UK. alangwade@fastmail.fm
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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