21080289

Source:http://linkedlifedata.com/resource/pubmed/id/21080289

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0005961, umls-concept:C0314627, umls-concept:C2323499, umls-concept:C2603343
pubmed:dateCreated	2010-11-16
pubmed:abstractText	Immune cells are derived from hematopoietic stem cells in the bone marrow. Experimental replacement of bone marrow offers the unique possibility to replace immune cells, to study gene function in mouse models of disease. Over the past decades, this technique has been used extensively to study, for instance, macrophage function in atherosclerosis. In this chapter, we describe the methods for both full bone marrow transplantations and T cell-specific transfers.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9214969
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:issn	1940-6029
pubmed:author	pubmed-author:HeeringaPeterP, pubmed-author:de WintherMenno P JMP
pubmed:issnType	Electronic
pubmed:volume	693
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	309-20
pubmed:meshHeading	pubmed-meshheading:21080289-Animals, pubmed-meshheading:21080289-Bone Marrow Transplantation, pubmed-meshheading:21080289-Cells, Cultured, pubmed-meshheading:21080289-Hematopoietic Stem Cells, pubmed-meshheading:21080289-Mice, pubmed-meshheading:21080289-T-Lymphocytes
pubmed:year	2011
pubmed:articleTitle	Bone marrow transplantations to study gene function in hematopoietic cells.
pubmed:affiliation	Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. Dewinther@GEN.unimaas.nl
pubmed:publicationType	Journal Article