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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-2-17
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pubmed:abstractText |
Naturally occurring regulatory T cells (Treg) are essential for the prevention of autoimmunity and overshooting immune responses to pathogens; however, the involvement of Treg in mesangioproliferative glomerulonephritis, a major cause of chronic kidney disease, remains unclear. Superagonistic CD28-specific monoclonal antibodies (CD28SA) are highly effective activators of Treg in rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1437-7799
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pubmed:author |
pubmed-author:HünigThomasT,
pubmed-author:IsakaYoshitakaY,
pubmed-author:KaimoriJunyaJ,
pubmed-author:KawachiHiroshiH,
pubmed-author:KimuraTomonoriT,
pubmed-author:KitamuraHarumiH,
pubmed-author:LiXiao-KangXK,
pubmed-author:MiyasatoKenroK,
pubmed-author:RakugiHiromiH,
pubmed-author:TakabatakeYoshitsuguY,
pubmed-author:TakaharaShiroS
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pubmed:issnType |
Electronic
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
50-7
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pubmed:meshHeading |
pubmed-meshheading:21076989-Animals,
pubmed-meshheading:21076989-Antibodies, Monoclonal,
pubmed-meshheading:21076989-Antigens, CD28,
pubmed-meshheading:21076989-Creatinine,
pubmed-meshheading:21076989-Glomerulonephritis, Membranoproliferative,
pubmed-meshheading:21076989-Lymphocyte Activation,
pubmed-meshheading:21076989-Male,
pubmed-meshheading:21076989-Proteinuria,
pubmed-meshheading:21076989-Rats,
pubmed-meshheading:21076989-Rats, Wistar,
pubmed-meshheading:21076989-T-Lymphocytes, Regulatory
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pubmed:year |
2011
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pubmed:articleTitle |
CD28 superagonist-induced regulatory T cell expansion ameliorates mesangioproliferative glomerulonephritis in rats.
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pubmed:affiliation |
Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.
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pubmed:publicationType |
Journal Article
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