Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-5
pubmed:dateCreated
2010-11-10
pubmed:abstractText
This study aimed to identify the signaling pathway for the proposed link between phosphodiesterase-5A (PDE5A) inhibition and decreased cardiac Na(+)/H(+) exchanger (NHE-1) activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Butadienes, http://linkedlifedata.com/resource/pubmed/chemical/Cyclic Nucleotide..., http://linkedlifedata.com/resource/pubmed/chemical/Dicarboxylic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3, http://linkedlifedata.com/resource/pubmed/chemical/Nitriles, http://linkedlifedata.com/resource/pubmed/chemical/Okadaic Acid, http://linkedlifedata.com/resource/pubmed/chemical/Pde5a protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Phosphodiesterase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Piperazines, http://linkedlifedata.com/resource/pubmed/chemical/Protein Phosphatase 1, http://linkedlifedata.com/resource/pubmed/chemical/Protein Phosphatase 2, http://linkedlifedata.com/resource/pubmed/chemical/Purines, http://linkedlifedata.com/resource/pubmed/chemical/Ribosomal Protein S6 Kinases, 90-kDa, http://linkedlifedata.com/resource/pubmed/chemical/Sodium-Hydrogen Antiporter, http://linkedlifedata.com/resource/pubmed/chemical/Sulfones, http://linkedlifedata.com/resource/pubmed/chemical/U 0126, http://linkedlifedata.com/resource/pubmed/chemical/endothall, http://linkedlifedata.com/resource/pubmed/chemical/growth factor-activatable Na-H..., http://linkedlifedata.com/resource/pubmed/chemical/sildenafil
pubmed:status
MEDLINE
pubmed:issn
1421-9778
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 S. Karger AG, Basel.
pubmed:issnType
Electronic
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
531-40
pubmed:meshHeading
pubmed-meshheading:21063091-Acidosis, pubmed-meshheading:21063091-Animals, pubmed-meshheading:21063091-Butadienes, pubmed-meshheading:21063091-Cyclic Nucleotide Phosphodiesterases, Type 5, pubmed-meshheading:21063091-Dicarboxylic Acids, pubmed-meshheading:21063091-Hydrogen-Ion Concentration, pubmed-meshheading:21063091-Mitogen-Activated Protein Kinase 1, pubmed-meshheading:21063091-Mitogen-Activated Protein Kinase 3, pubmed-meshheading:21063091-Nitriles, pubmed-meshheading:21063091-Okadaic Acid, pubmed-meshheading:21063091-Papillary Muscles, pubmed-meshheading:21063091-Phosphodiesterase Inhibitors, pubmed-meshheading:21063091-Phosphorylation, pubmed-meshheading:21063091-Piperazines, pubmed-meshheading:21063091-Protein Phosphatase 1, pubmed-meshheading:21063091-Protein Phosphatase 2, pubmed-meshheading:21063091-Purines, pubmed-meshheading:21063091-Rats, pubmed-meshheading:21063091-Ribosomal Protein S6 Kinases, 90-kDa, pubmed-meshheading:21063091-Sodium-Hydrogen Antiporter, pubmed-meshheading:21063091-Sulfones
pubmed:year
2010
pubmed:articleTitle
Phosphodiesterase 5A inhibition decreases NHE-1 activity without altering steady state pH(i): role of phosphatases.
pubmed:affiliation
Centro de Investigaciones Cardiovasculares, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't