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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-11-9
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pubmed:abstractText |
POU class 2 homeobox 1 (POU2F1), also known as octamer-binding transcription factor-1 (OCT-1), is a ubiquitous transcription factor that plays a key role in the regulation of genes related to inflammation and cell cycles. POU2F1 is located on chromosome 1q24, a region with linkage for Type 2 diabetes in Chinese and other populations. We examined the association of POU2F1 genetic variants with Type 2 diabetes in Hong Kong Chinese using two independent cohorts.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1464-5491
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pubmed:author |
pubmed-author:ChanA W HAW,
pubmed-author:ChanJ C NJC,
pubmed-author:HoII,
pubmed-author:International Type 2 Diabetes 1q Consortium,
pubmed-author:JiaW PWP,
pubmed-author:LamV K LVK,
pubmed-author:MaR C WRC,
pubmed-author:MakW WWW,
pubmed-author:NgM C YMC,
pubmed-author:SoW-YWY,
pubmed-author:TamC H TCH,
pubmed-author:TongP C YPC,
pubmed-author:WangC RCR,
pubmed-author:WayeM M YMM,
pubmed-author:ZeeB C YBC
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pubmed:copyrightInfo |
© 2010 The Authors. Diabetic Medicine © 2010 Diabetes UK.
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1443-9
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pubmed:meshHeading |
pubmed-meshheading:21059098-Adult,
pubmed-meshheading:21059098-Asian Continental Ancestry Group,
pubmed-meshheading:21059098-Diabetes Mellitus, Type 2,
pubmed-meshheading:21059098-Female,
pubmed-meshheading:21059098-Genetic Linkage,
pubmed-meshheading:21059098-Genetic Predisposition to Disease,
pubmed-meshheading:21059098-Genotype,
pubmed-meshheading:21059098-Hong Kong,
pubmed-meshheading:21059098-Humans,
pubmed-meshheading:21059098-Male,
pubmed-meshheading:21059098-Middle Aged,
pubmed-meshheading:21059098-Octamer Transcription Factor-1,
pubmed-meshheading:21059098-Phylogeny,
pubmed-meshheading:21059098-Polymorphism, Single Nucleotide,
pubmed-meshheading:21059098-Risk Factors,
pubmed-meshheading:21059098-Transcription Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Association of the POU class 2 homeobox 1 gene (POU2F1) with susceptibility to Type 2 diabetes in Chinese populations.
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pubmed:affiliation |
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China. maggieng@cuhk.edu.hk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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