|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:dateCreated |
2010-11-29
|
|
pubmed:abstractText |
Respiratory infections including Mycoplasma pneumoniae (Mp) contribute to various chronic lung diseases. We have shown that mouse short palate, lung, and nasal epithelium clone 1 (SPLUNC1) protein was able to inhibit Mp growth. Further, airway epithelial cells increased SPLUNC1 expression upon Mp infection. However, the mechanisms underlying SPLUNC1 regulation remain unknown. In the current study, we investigated if SPLUNC1 production following Mp infection is regulated through Toll-like receptor 2 (TLR2) signaling.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/BPIFA1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Bpifa1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/TLR2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tlr2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 2
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1465-993X
|
|
pubmed:author |
pubmed-author:CaseStephanieS,
pubmed-author:ChuHong WeiHW,
pubmed-author:GallyFabienneF,
pubmed-author:Janssen-HeiningerYvonne MYM,
pubmed-author:JiangDiD,
pubmed-author:MartinRichard JRJ,
pubmed-author:MichelsNicoleN,
pubmed-author:MinorMaishaM,
pubmed-author:ReisdorphNicholeN,
pubmed-author:SimonGlennG,
pubmed-author:SmithSeanS,
pubmed-author:ThaikoottathilJyotiJ,
pubmed-author:WuQunQ,
pubmed-author:ZhangGongyiG
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
155
|
|
pubmed:dateRevised |
2011-10-14
|
|
pubmed:meshHeading |
pubmed-meshheading:21054862-Animals,
pubmed-meshheading:21054862-Cells, Cultured,
pubmed-meshheading:21054862-Epithelial Cells,
pubmed-meshheading:21054862-Gene Expression Regulation,
pubmed-meshheading:21054862-Glycoproteins,
pubmed-meshheading:21054862-Humans,
pubmed-meshheading:21054862-Mice,
pubmed-meshheading:21054862-Phosphoproteins,
pubmed-meshheading:21054862-Pneumonia, Mycoplasma,
pubmed-meshheading:21054862-Respiratory Mucosa,
pubmed-meshheading:21054862-Toll-Like Receptor 2
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
SPLUNC1 regulation in airway epithelial cells: role of Toll-like receptor 2 signaling.
|
|
pubmed:affiliation |
Department of Medicine, National Jewish Health, and the University of Colorado Denver, Denver, CO, USA. chuhw@njhealth.org
|
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|
