|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0013227,
umls-concept:C0032854,
umls-concept:C0033325,
umls-concept:C0033684,
umls-concept:C0035647,
umls-concept:C0205245,
umls-concept:C1283195,
umls-concept:C1521725,
umls-concept:C1521840,
umls-concept:C1521991,
umls-concept:C1561558,
umls-concept:C1879547,
umls-concept:C1882071
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2010-11-2
|
|
pubmed:abstractText |
In spite of leukemia therapy improvements obtained over the last decades, therapy is not yet effective in all cases. Current approaches in Acute Lymphoblastic Leukemia (ALL) research focus on identifying new molecular targets to improve outcome for patients with a dismal prognosis. In this light phosphoproteomics seems to hold great promise for the identification of proteins suitable for targeted therapy.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1932-6203
|
|
pubmed:author |
pubmed-author:AccordiBenedettaB,
pubmed-author:BassoGiuseppeG,
pubmed-author:De MariaRuggeroR,
pubmed-author:EspinaVirginiaV,
pubmed-author:GallaLuisaL,
pubmed-author:GiordanMarcoM,
pubmed-author:LiottaLanceL,
pubmed-author:MilaniGloriaG,
pubmed-author:PetricoinEmanuelE,
pubmed-author:RuzzeneMariaM,
pubmed-author:SciroManuelaM,
pubmed-author:TrentinLucaL,
pubmed-author:VanMeterAmyA,
pubmed-author:te KronnieGeertruyG
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
5
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
e13552
|
|
pubmed:meshHeading |
pubmed-meshheading:21042412-Adenylate Kinase,
pubmed-meshheading:21042412-Blotting, Western,
pubmed-meshheading:21042412-Cell Line, Tumor,
pubmed-meshheading:21042412-Child,
pubmed-meshheading:21042412-Child, Preschool,
pubmed-meshheading:21042412-Humans,
pubmed-meshheading:21042412-Immunoprecipitation,
pubmed-meshheading:21042412-Infant,
pubmed-meshheading:21042412-Leukemia, B-Cell,
pubmed-meshheading:21042412-Neoplasm Proteins,
pubmed-meshheading:21042412-Prednisone,
pubmed-meshheading:21042412-Prognosis,
pubmed-meshheading:21042412-Proteomics,
pubmed-meshheading:21042412-Signal Transduction
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL.
|
|
pubmed:affiliation |
Oncohematology Laboratory, Department of Pediatrics, University of Padova, Padova, Italy. benedetta.accordi@unipd.it
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
