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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2010-11-2
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pubmed:abstractText |
The binucleation of hepatocytes, which was known as an important feature of liver growth and physiology, has been reported to be increased during the chronic oxidative injury stage and has been regarded as an age-related change of hepatic structures. Therefore, we investigated the binuclearity pattern in the livers of senescence marker proteins-30 (SMP30) knock-out (KO) mice compared with wild-type (WT) mice and vitamin C-treated KO (KO + VC) mice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1440-1746
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pubmed:author |
pubmed-author:ChungHae-YoungHY,
pubmed-author:GooMoon-JungMJ,
pubmed-author:HongIl-HwaIH,
pubmed-author:IshigamiAkihitoA,
pubmed-author:JeongKyu-ShikKS,
pubmed-author:JiAe-RiAR,
pubmed-author:KiMi-RanMR,
pubmed-author:KimDong-HwanDH,
pubmed-author:KwakJi-HoonJH,
pubmed-author:LeeSeung-SookSS,
pubmed-author:MinChang-WooCW,
pubmed-author:ParkJin-KyuJK
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pubmed:copyrightInfo |
Journal compilation © 2010 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1769-76
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pubmed:meshHeading |
pubmed-meshheading:21039840-Analysis of Variance,
pubmed-meshheading:21039840-Animals,
pubmed-meshheading:21039840-Ascorbic Acid Deficiency,
pubmed-meshheading:21039840-Body Weight,
pubmed-meshheading:21039840-Calcium-Binding Proteins,
pubmed-meshheading:21039840-Cell Nucleus,
pubmed-meshheading:21039840-Cytochrome P-450 CYP2E1,
pubmed-meshheading:21039840-Hepatocytes,
pubmed-meshheading:21039840-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:21039840-Lipid Peroxidation,
pubmed-meshheading:21039840-Male,
pubmed-meshheading:21039840-Mice,
pubmed-meshheading:21039840-Mice, Knockout,
pubmed-meshheading:21039840-Oxidative Stress,
pubmed-meshheading:21039840-Reactive Oxygen Species,
pubmed-meshheading:21039840-Up-Regulation
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pubmed:year |
2010
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pubmed:articleTitle |
Vitamin C deficiency increases the binucleation of hepatocytes in SMP30 knock-out mice.
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pubmed:affiliation |
Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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