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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
Database issue
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pubmed:dateCreated |
2010-12-23
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pubmed:abstractText |
The Universal PBM Resource for Oligonucleotide-Binding Evaluation (UniPROBE) database is a centralized repository of information on the DNA-binding preferences of proteins as determined by universal protein-binding microarray (PBM) technology. Each entry for a protein (or protein complex) in UniPROBE provides the quantitative preferences for all possible nucleotide sequence variants ('words') of length k ('k-mers'), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In this update, we describe >130% expansion of the database content, incorporation of a protein BLAST (blastp) tool for finding protein sequence matches in UniPROBE, the introduction of UniPROBE accession numbers and additional database enhancements. The UniPROBE database is available at http://uniprobe.org.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-10812473,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-11404456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-14709165,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-15543148,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-16381825,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-16998473,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-18541913,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-18585359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-18681939,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-18842628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-18971253,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-19147588,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-19158363,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-19204119,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-19443739,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-19632181,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-19906716,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-2231712,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21037262-9254694
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1362-4962
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
D124-8
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pubmed:dateRevised |
2011-7-20
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pubmed:meshHeading |
pubmed-meshheading:21037262-Animals,
pubmed-meshheading:21037262-Binding Sites,
pubmed-meshheading:21037262-DNA,
pubmed-meshheading:21037262-DNA-Binding Proteins,
pubmed-meshheading:21037262-Databases, Protein,
pubmed-meshheading:21037262-Humans,
pubmed-meshheading:21037262-Internet,
pubmed-meshheading:21037262-Protein Array Analysis,
pubmed-meshheading:21037262-Sequence Analysis, Protein,
pubmed-meshheading:21037262-Software
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pubmed:year |
2011
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pubmed:articleTitle |
UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on protein-DNA interactions.
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pubmed:affiliation |
Department of Medicine, Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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