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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
17-18
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pubmed:dateCreated |
2010-11-15
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pubmed:abstractText |
The substituted pterocarpenes named aracarpene-1 (1) and aracarpene-2 (2) were isolated from wounded peanut seeds challenged by a strain of Aspergillus caelatus. The structures of these putative phytoalexins were determined by interpretation of NMR and MS data. The aracarpenes were investigated for their antifungal and antibacterial activities as well as antioxidant, anti-inflammatory, and cytotoxic activities in mammalian cells. Aracarpene-2 demonstrated high antibacterial properties against tested gram-positive and gram-negative bacteria, whereas aracarpene-1 displayed low antibacterial properties against the same bacteria. Both compounds had no antifungal activity against Aspergillus flavus. Together with peanut stilbenoids that are also produced in the challenged seeds, these compounds may represent a class of low-molecular weight peanut metabolites with a defensive role(s) against pathogenic microorganisms.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1873-3700
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pubmed:author |
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pubmed:copyrightInfo |
Published by Elsevier Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2099-107
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pubmed:meshHeading |
pubmed-meshheading:21030054-Animals,
pubmed-meshheading:21030054-Anti-Bacterial Agents,
pubmed-meshheading:21030054-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:21030054-Antifungal Agents,
pubmed-meshheading:21030054-Antineoplastic Agents,
pubmed-meshheading:21030054-Arachis hypogaea,
pubmed-meshheading:21030054-Aspergillus,
pubmed-meshheading:21030054-Botrytis,
pubmed-meshheading:21030054-Cercopithecus aethiops,
pubmed-meshheading:21030054-Colletotrichum,
pubmed-meshheading:21030054-Fusarium,
pubmed-meshheading:21030054-Humans,
pubmed-meshheading:21030054-Microbial Sensitivity Tests,
pubmed-meshheading:21030054-Molecular Structure,
pubmed-meshheading:21030054-NF-kappa B,
pubmed-meshheading:21030054-Nitric Oxide,
pubmed-meshheading:21030054-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:21030054-Pterocarpans,
pubmed-meshheading:21030054-Reactive Oxygen Species,
pubmed-meshheading:21030054-Seeds,
pubmed-meshheading:21030054-Vero Cells
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pubmed:year |
2010
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pubmed:articleTitle |
Pterocarpenes elicited by Aspergillus caelatus in peanut (Arachis hypogaea) seeds.
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pubmed:affiliation |
National Peanut Research Laboratory, Agricultural Research Service, US Department of Agriculture, Dawson, GA 39842, USA. victor.sobolev@ars.usda.gov
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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