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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1991-9-17
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pubmed:abstractText |
A dose response procedure was developed for evaluating vitamin A status and utilization in cattle. This could be useful for evaluating diets, vitamin A stores and homeostatic control of vitamin A. Three experiments were designed to determine: 1) size of vitamin A dose required to increase plasma vitamin A concentrations; 2) time after dosing when plasma vitamin A concentrations peak, and 3) if changes in plasma vitamin A concentrations are useful in assessing dietary vitamin A utilization. Using twenty-four steers and heifers, the first two experiments showed that 30X or 40X daily vitamin A requirement (daily requirement calculated as X = body weight in kilograms times 55 International Units of vitamin A) given orally was sufficient to cause plasma vitamin A concentrations to rise 20 hours after dosing. Plasma vitamin A concentrations increased (P less than .01) from 57 to 81 micrograms/dl and 64 to 84 micrograms/dl after a 30X or 40X treatment, respectively. Twenty-X daily requirement resulted in a slight increase after 20 hours (P greater than .05). Seventy-two feedlot steers were used in experiment three to determine if diet affects vitamin A dose response. Variations in feed intake, monensin in the diet or a single dose of vitamin E did not cause significant changes in plasma vitamin A response to vitamin A dosage. Steers receiving monensin had higher initial plasma vitamin A concentrations, but no differences were observed after dosing. Results indicate that dose responses may be useful in assessing dietary vitamin A utilization.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-9831
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
314-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2101822-Administration, Oral,
pubmed-meshheading:2101822-Animal Nutritional Physiological Phenomena,
pubmed-meshheading:2101822-Animals,
pubmed-meshheading:2101822-Body Weight,
pubmed-meshheading:2101822-Cattle,
pubmed-meshheading:2101822-Dose-Response Relationship, Drug,
pubmed-meshheading:2101822-Nutritional Status,
pubmed-meshheading:2101822-Vitamin A
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pubmed:year |
1990
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pubmed:articleTitle |
Plasma vitamin A levels in cattle in response to large doses of vitamin A.
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pubmed:affiliation |
Department of Animal Science, University of Kentucky, Lexington 40546.
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pubmed:publicationType |
Journal Article
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