|
rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
3
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pubmed:dateCreated |
1978-10-18
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pubmed:abstractText |
Glucose-6-phosphatase (G-6-Pase) activity in liver and blood platelets of two patients with glycogen storage disease (GSD) type I is described. Both patients had a reduced activity of G-6-Pase in liver. The km value for glucose 6-phosphate (G-6-P) of residual activity in liver of both patients was similar to that of control liver. We could not demonstrate any reduced activity of platelet G-6-Pase in the patients. Platelet G-6-Pase with our assay method seems to represent a nonspecific phosphatase activity. Our observation suggests that it is necessary to examine platelet G-6-Pase of many other patients with GSD type I to confirm that G-6-Pase deficiency can be diagnosed by enzyme assay performed on blood platelets.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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|
pubmed:month |
Aug
|
|
pubmed:issn |
0009-8981
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:day |
1
|
|
pubmed:volume |
87
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
319-26
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:209906-Alanine,
pubmed-meshheading:209906-Blood Glucose,
pubmed-meshheading:209906-Blood Platelets,
pubmed-meshheading:209906-Child, Preschool,
pubmed-meshheading:209906-Female,
pubmed-meshheading:209906-Galactose,
pubmed-meshheading:209906-Glucagon,
pubmed-meshheading:209906-Glucose-6-Phosphatase,
pubmed-meshheading:209906-Glycerophosphates,
pubmed-meshheading:209906-Glycogen Storage Disease Type I,
pubmed-meshheading:209906-Humans,
pubmed-meshheading:209906-Liver,
pubmed-meshheading:209906-Liver Glycogen
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|
pubmed:year |
1978
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|
pubmed:articleTitle |
Glucose-6-phosphatase activity in liver and blood platelets of two patients with glycogen storage disease type I.
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|
pubmed:publicationType |
Journal Article,
Case Reports
|
