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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2010-10-19
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pubmed:abstractText |
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related chemicals. The AhR influences a variety of processes involved in cellular growth and differentiation, and recent studies have suggested that the AhR is a potential target for immune-mediated diseases.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:BissonWilliam HWH,
pubmed-author:FarrerDavidD,
pubmed-author:KerkvlietNancy INI,
pubmed-author:KochDaniel CDC,
pubmed-author:KolluriSiva KumarSK,
pubmed-author:KopparapuPrasad RPR,
pubmed-author:MathewLijoy KLK,
pubmed-author:O'DonnellEdmond FEF,
pubmed-author:SailiKaterine SKS,
pubmed-author:SenguptaSumitraS,
pubmed-author:TanguayRobert LRL
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:meshHeading |
pubmed-meshheading:20957046-Animals,
pubmed-meshheading:20957046-Anti-Inflammatory Agents,
pubmed-meshheading:20957046-Base Sequence,
pubmed-meshheading:20957046-Cell Line,
pubmed-meshheading:20957046-Cytochrome P-450 CYP1A2,
pubmed-meshheading:20957046-DNA Primers,
pubmed-meshheading:20957046-Fluorescent Antibody Technique,
pubmed-meshheading:20957046-Genes, Reporter,
pubmed-meshheading:20957046-Isoxazoles,
pubmed-meshheading:20957046-Ligands,
pubmed-meshheading:20957046-Mice,
pubmed-meshheading:20957046-Mice, Inbred C57BL,
pubmed-meshheading:20957046-Polymerase Chain Reaction,
pubmed-meshheading:20957046-Receptors, Aryl Hydrocarbon,
pubmed-meshheading:20957046-Regeneration,
pubmed-meshheading:20957046-Zebrafish
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pubmed:year |
2010
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pubmed:articleTitle |
The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor.
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pubmed:affiliation |
Cancer Research Laboratory, Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon, United States of America.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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