Linked Life Data

20946367

Source:http://linkedlifedata.com/resource/pubmed/id/20946367

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-10-15
pubmed:abstractText
The revelation of the human genome has enabled scientists to assess the disposition and response of an organism to an environmental stimulus; transcriptomics, proteomics, and metabonomics can each generate such holistic views. Nutrigenomic techniques help researchers elucidate individual responses to nutritional interventions holistically and help with the design of personalized diets adapted to individual needs. Human genetics has revealed insights into health and disease susceptibility and can help differentiate responders from nonresponders in dietary interventions, but the predictive power of single-nucleotide polymorphisms in disease susceptibility genes has so far been limited in terms of helping to foresee a health trajectory. Epigenetics encompasses alterations of genetic material that do not affect the DNA nucleotide sequence; these include DNA methylation patterns, chromatin structure, histone codes, and non-coding small RNAs. DNA methylation is modified particularly around the time of birth; therefore, early-life nutrition may affect health outcomes later in life.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1753-4887
pubmed:author
pubmed:copyrightInfo
© 2010 ILSI Europe.
pubmed:issnType
Electronic
pubmed:volume
68 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S38-47
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Nutrigenomics: where are we with genetic and epigenetic markers for disposition and susceptibility?
pubmed:affiliation
Functional Genomics Group, Nestlé Research Center, Lausanne, Switzerland.
pubmed:publicationType
Journal Article, Review